Oncology Abstracts

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Estrogen receptor regulated miR-342 suppresses a pro-metastatic gene network

Lumb Rachael , Arnet Victoria K , Johnstone Cameron N , Pillman Katherine A , Toubia John , Hackett-Jones Emily , Phillips Caroline A , Pinweha Pannapa , Roslan Suraya , Li Xiaochun , Beilharz Traude , Khew-Goodall Yeesim , Goodall Gregory J , Anderson Robin L , Gregory Philip A

Breast cancer is the most frequently diagnosed cancer in women and the second leading cause of female cancer related death. Despite significant advances in early detection, surgery and therapy, treatment remains a challenge if metastatic disease develops. Metastasis occurs with high frequency in triple negative (ER/PR/HER2 negative, TNBC) breast cancers, which are a heterogeneous group of cancers with poor clinical outcome. We used an integrated approach to identify miRNAs tha...

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Expression of the interleukin-3/receptor complex by breast cancer cells promotes vascular mimicry via a PI3K-dependent mechanism and is associated with poor outcome

Thompson Emma J , Duluc Camille , Barry Emma F , Farshid Gelareh , Simpson Kaylene J , Gregory Phillip A , Li Xiaochun , Madden Stephen , Owczarek Cathy M , Wilson Nick J , Vairo Gino , Nash Andrew D , Ingman Wendy V , Lindeman Geoffrey J , Lim Elgene , Khew-Goodall Yeesim , Lopez Angel F , Bonder Claudine S

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Oncology Abstracts

Estrogen receptor regulated miR-342 suppresses a pro-metastatic gene network

Expression of the interleukin-3/receptor complex by breast cancer cells promotes vascular mimicry via a PI3K-dependent mechanism and is associated with poor outcome

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